Psychiatric Symptoms in Women with Focal Cervical Dystonia - Exploring New Pathophysiological Pathways
نویسندگان
چکیده
So far there is not much research considering female sex as a risk factor for developing focal cervical dystonia and concomitant psychiatric symptoms such anxiety. New proposes ideas of CD baseline pathophysiology targeting neurobiological mechanisms gamma aminobutyric acid GABAergic function underlying sexual dimorphism an intrinsic the disease itself. Our examines connection between motor non-motor in patients suffering from their response to treatment, cit- ing available literature hypothesising whether it can be linked previously described alterations GABA levels.
منابع مشابه
Lower serotonin transporter binding in patients with cervical dystonia is associated with psychiatric symptoms
BACKGROUND Cervical dystonia (CD) is often accompanied by depressive symptoms, anxiety, and jerks/tremor. The dopamine transporter (DAT) binding is related with both depressive symptoms and jerks/tremor in CD. Serotonergic and dopaminergic systems are closely related. As serotonin is involved in the pathophysiology of psychiatric symptoms and jerks, we expected an altered serotoninergic system ...
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We describe a 48-year-old woman with putaminal gliosis and a sphenoid wing meningioma at the left, who developed dystonia restricted to cervical regions. We propose the following causal chain: the meningioma led to an occlusion of a lenticulo-striatal branch of the middle cerebral artery that caused ventral putaminal ischemia and finally resulting in symptomatic dystonia. The previously reporte...
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We assessed the course of psychiatric disorders in 23 cervical dystonia patients by using the structured clinical interview for DSM-IV and different rating scales. Patients were studied on two occasions 5 years apart. There were no differences in psychiatric disorders and severity of psychiatric symptoms between the two evaluations, whereas the severity of dystonia was milder at the second eval...
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There is currently a general consensus of agreement that dystonia is a disease of the basal ganglia, although dystonic symptoms have been observed in association with lesions in various different sites of the sensory and motor pathways. 1 In particular, cervical in-tramedullary lesions have been reported as being a rare cause of focal hand dystonia, 2 although in these cases the pathogenesis of...
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BACKGROUND Primary focal dystonia and Parkinson's disease are movement disorders that have contrasting motor phenotypes. The aim of this study was to compare the frequency and the severity of psychiatric disorders in primary focal dystonia and Parkinson's disease. METHODS Two groups of 30 patients matched by gender and age underwent a neurological and psychiatric assessment. RESULTS Parkins...
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ژورنال
عنوان ژورنال: Archives of psychiatry research
سال: 2023
ISSN: ['2671-1079', '2671-2008']
DOI: https://doi.org/10.20471/may.2023.59.01.03